This symptom is a precursor to difficulty speaking. While the end result of this prank created a funny and memorable dinner party scene, the poisonous effects of eye drops are much more serious in real life. Reports of significant toxicity from tetrahydrozoline ingestion are unusual but have occured primarily in small children after unintentional ingestion (3-63, 6). She was a manager at Pizza Hut in 2011, when a disgruntled co-worker spiked her soda with eye drops. Founded in 1956, the University of Florida College of Nursing is the premier educational institution for nursing in the state of Florida and is ranked in the top 10 percent of all nursing graduate programs nationwide. Seems they use the eye medication Visine for a little Montezuma's revenge. Stephen Clayton, a millionaire businessman,lived with his wife in a South Carolina mansion that is a replica of George Washington's Mount Vernon plantation. is also a founding member of Hi-Ethics. Givens, Ann. Sinoatrial node arrest following tetrahydrozoline ingestion. Exposure is common in young children, who unintentionally ingest it, but cases have been rising in the adult population. Swenson K. His wife said he died falling down the stairs. Established in 1923, the College of Pharmacy is the oldest college in the UF Academic Health Center. There are certainly other better ways of giving someone explosive diarrhea, not that you should ever try to give someone such misery. Frequent numbness, tingling or a pins-and-needles sensation, usually in the hands. Also, the mental image of an enemy sent hotfooting for the toilet is a hugely satisfying one, especially in a society that views fecal output as something to be ashamed of. Dont do what the Owen Wilson character did in the movie Wedding Crashers. Clayton, you sure have tangled this one up, he said. It does NOT need to be an emergency. "Student Accused of Poison Attempt." WPVI-TV [Philadelphia]. 7, pp. Tetryzoline. More than 1,600 cases of oral exposures are reported to United States poison centers annually (1,2). There are approximately 130 cases of tetrahydrozoline exposure reported each year to the online poison control toolwebPOISONCONTROL. The imidazoline derivatives, oxymetazoline, xylometazoline, tetrahydrozoline, and naphazoline, are found in topical ophthalmic and nasal decongestants available OTC.They are generally used as topical vasoconstrictors in the nose and eyes for temporary relief of nasal congestion due to colds, hay fever or other upper respiratory allergies, or sinusitis. North County Gazette. "Central Nervous System Depression Following Accidental Ingestion of Visine Eye Drops." Symptoms of an overdose of tetrahydrozoline include drowsiness, slow breathing or absence of breathing, slow heartbeat, hypothermia and possibly even coma. Dont say wow so often. If you or someone you are with has an exposure, call the local emergency number (such as 911), or the local poison center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. Alexis Jennings, of Natrona County, entered the plea Thursday in state district court. Automobile fluids. King World Productions Inc. 2023 Inside Edition Inc. and CBS interactive Inc., Paramount companies. Tetrahydrozoline, a derivative of imidazoline, is widely used for the symptomatic relief of conjunctival and nasal congestion; however, intentional or unintentional high doses can result in toxicity manifested by hypotension, tachycardia, and CNS depression. UF Health scientist lands first-ever NIH grant for a rare disorder devastating UF Health joins national effort to improve patient outcomes. Police say she poisoned him- with eye drops. Ranked among the top schools of pharmacy nationally, the college supports research, service and educational programs enhanced with online technologies. Journal of forensic sciences, 57(3), 835-838. 52 VANDERBILT AVE, NEW YORK, NY 10017 USA: INFORMA HEALTHCARE. Flynn, George. Waltham, MA: Elsevier; 2016:793. Ms. Tomassoni, A. J. Reza, H.G. All local poison control centers in the United States use this national number. Ms. Clayton had originally been charged with murder after her arrest in August 2018, the arrest warrant said. In a scene from the 2005 movie Wedding Crashers, Owen Wilsons character adds eye drops to another characters drink with the intent of causing gastrointestinal discomfort and diarrhea. Alpha-2 Adrenergic and Imidazoline Receptor Agonists: Clonidine, Dexmedetomidine, and Related Antihypertensives, Decongestants, and Sedatives. This national hotline will let you talk to experts in poisoning. That can be like taking ibuprofen for pain caused by a harpoon stuck in you without first saying, maybe, I should do something about this harpoon stuck in me.. Next got in a car accident and died. The Lancet. How Visine eye drops in the mouth can kill, here are two cases. They will give you further instructions. The. The products contain the active ingredients tetrahydrozoline, naphazoline, or oxymetazoline. Take the container with you to the hospital, if possible. You should call if you have any questions about poisoning or poison prevention. Everyone who has ever been wronged has at one time or another felt the urge to strike a counterblow. "Severe Nausea and Vomiting with Timolol Eye Drops." I never thought it would kill him.. Anyone can read what you share. According to Michael Banks, reporting for the Shelby Star, Hunsucker had resisted an autopsy being done before his wifes body was cremated. 25.1K subscribers Lana Sue Clayton used Visine eye drops to poison her husband, Steven Clayton. Pictured here are boxes of Visine, over-the-counter eye drops produced by Johnson & Johnson. 1-800-222-1222 Most recently, a California man was arrested a week ago and charged with trying to poison his girlfriend by lacing her drinks with the eye drops. Tetrahydrozoline Poisoning can be prevented by: It is important to give your healthcare provider a complete list of prescription and non-prescription medications that are being currently taken. Since blood is red, unless you are Vulcan, less blood may mean less redness. Editorial team. stinging or burning of the eye blurred vision increased eye redness or irritation If you experience any of the following symptoms, stop using tetrahydrozoline eye drops and call your doctor immediately: headache sweating fast or irregular heartbeat nervousness Dont do most things that he did. Nardo, Melissa. Call 911 for all medical emergencies. Otherwise, theyd be called other orifice drops. They are also called drops and not buckets because you are only supposed to use limited amounts. Police said Lana Clayton poisoned her 64-year-old husband, Stephen, with eye drops. Lana Sue Clayton in a 2018 booking photo. Clonidine and topical imidazolines exposure in toddlers. J Emerg Med. Murdaugh is heckled as he leaves court, Ukrainian soldier takes out five tanks with Javelin missiles, Isabel Oakeshott receives 'menacing' message from Matt Hancock, Alex Murdaugh unanimously found GUILTY of murder of wife and son, Isabel Oakeshott clashes with Nick Robinson over Hancock texts, Family of a 10-month-old baby filmed vaping open up, Missing hiker buried under snow forces arm out to wave to helicopter, Moment teenager crashes into back of lorry after 100mph police race. The main systemic effects are . Dog poisoning symptoms include: Vomiting Lethargy Abdominal pain Loss of appetite Excessive salivation Lack of coordination Bloody urine Causes Overdosing of veterinary pills Consumption of human drugs including but not limited to: Antihistamines Sleeping tablets Diet pills Heart pills Blood pressure pills Ibuprofen Acetaminophen Diagnosis Then, they were forced to leave a bar by the person who posioned them. I felt awful, she told Inside Edition. This article is for information only. Tetrahydrozoline is a form of a medicine called imidazoline, which is found in over-the-counter eye drops and nasal sprays. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. I will drop in updates here accordingly. Some common symptoms that might point to a poisoning include: Nausea and . "If I had an underlying medical condition or if I had gotten a little more of the drug I could have been. The poisonous effect made headlines when Lana Clayton, 52, wascharged for murdering her husband by adding redness-relieving eye drops to his drinking water for three days. This would not be a good prank. Yet it is not only toddlers who risk central nervous system shutdown or other dire results if they swallow Visine, as demonstrated by the following examples: Revenge seekers still not quite convinced that a Visine mickey finn won't produce the diarrheal results they crave, or that the drinking of such a potion could potentially result in a life-threatening medical crisis in the object of their prank, should consider one final fact: the act of secreting noxious substances in ingestibles for the purpose of bringing harm to others is called poisoning. Copyright 1997-2023, A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited without authorization. "Woman Accused of Trying to Kill Husband." Co-located with the Shands Jacksonville Hospital, the Jacksonville Health Science Center excels in education, research and patient care that expresses our abiding values of compassion, excellence, professionalism and innovation. Death comes in the form of paralysis-your mind is wide awake, but . UpToDate.Topic 16258 Version 15.0, November 2020. Journal of Medical Toxicology, 10(4), 388-391. In 1996, a two-year-old child who ingested at most 2 to 3 mL of Visine eye drops became dangerously lethargic and unresponsive to every stimulus except deep pain. Loosen tight clothing such as a collar, tie, belt or waistband. "Visine Prank Leads to Day in Court." A 33-year-old Pennsylvania woman could spend the rest of her life in prison after admitting to police that she repeatedly poisoned her boyfriend with Visine eye drops for more than three years in . The active component in Visine eye drops is tetrahydrozoline. I am a writer, journalist, professor, systems modeler, computational and digital health expert, avocado-eater, and entrepreneur, not always in that order. On Thursday, the woman, Lana Sue Clayton, 53, a former Veterans Affairs nurse, was sentenced to 25 years in prison for killing her husband, Stephen D. Clayton, 64, at their home in Clover, S.C., the documents show. In March 2013, a 27-year-old mechanic named Shayne Carpenter was arrested in Grass Valley, California, for putting eye drops in his girlfriend's drink after an argument with her, causing her to feel ill. state Department of Insurance said when announcing his arrest last month. and Ph.D. degrees in Veterinary Medical Sciences. University of Florida Health knows how important ongoing medical learning is to health care providers and the community. These medications are available over-the-counter in pharmacies in the United States and are frequently not packaged in child-resistant containers. Joshua Lee Hunsucker, 35, on Thursday was charged with first-degree murder in the September 2018 death of his . Foreign objects like batteries and toys. That same month, an autopsy by Waukesha County Medical Examiner Linda Biedrzycki showed that Hernan had a fatal dose of tetrahydrozolinethe main ingredient in over-the-counter eye dropsin her system. Ginger Watson knows what it is like to be poisoned by eye drops. (Photo: Getty Images). 20 February 2002. Seek medical help right away. Also offered on campus is an American Society of Health-System Pharmacists-accredited pharmacy residency program at Shands Jacksonville. The girlfriend later discovered that Carpenter had been texting his friends to boast about the eye drops prank and called the police on him. While poisoning symptoms are uncommon after applying the drops to the eyes, these agents can produce significant poisoning if taken orally. Investigators have said Jennings wanted her stepmother dead because the teen told the woman she had molested a young girl, and the stepmother revealed the secret to Jennings' then-boyfriend. [Medford, OR] Mail Tribune. WRIC-TV [Richmond]. Program completed entirely in Jacksonville. The College of Medicine, the largest of six colleges at the University of Florida Academic Health Center, opened in 1956 with a mission to increase Florida's supply of highly qualified physicians, provide advanced health-care services to Florida residents and foster discovery in health research. You could kill the person. 22 May 2002. Stars and Stripes. Together we teach. Stop using Visine and call your doctor at once if you have: ongoing or worsening eye redness; eye pain; changes in your vision; Thats why you dont typically eat your contact lens. I felt awful," she told Inside Edition. , the 53-year-old Clayton pled guilty tovoluntary manslaughter and tampering with a food or drug after she admitted togiving her husband Steven Clayton drinks laced with Visine.. (Photo [+] by Roberto Machado Noa/LightRocket via Getty Images). It is a member of the imidazole family that can serve as decongestants and vasoconstrictors. Gentissi experienced vomiting and bleeding from his rectum, and Anzalone eventually agreed to a plea bargain with prosecutors under which she was ordered to pay $10,000 in hospital bills, serve three years' probation, and obey an order of protection. As this ABC News segment described, he allegedly used Visine eye drops to poison and eventually kill his wife, 32-year-old Stacy Robinson Hunsucker: Per the news segment, Hunsucker and his wife had been high school sweethearts. While it is true that Visine is readily obtainable (it's an non-prescription eye drop manufactured by pharmaceutical giant Pfizer), a drink spiked with it is not a sure-fire means of producing diarrhea in the one unfortunate enough to swallow it, and ingestion of such a concoction is downright dangerous, making this "harmless" form of retaliation fraught with hazard. Yet if Visine doesn't cause diarrhea, it has done things far more terrible. Sometimes poison doesn't cause any symptoms. In January 2015 Unger pleaded guilty to six counts of aggravated assault of a victim less than six years old and one count of endangering the welfare of a child. Alcohol. It then grabs onto the surface of your cat's red blood cells in the spots normally used to carry oxygen to the tissues. Officials told K2Radio the girl varied her dosage of the eye drops poured into her stepmothers beverages from as little as one-sixth of a bottle to as much as a quarter of a bottle. Clayton's family released a statement on the allegations against his wife. Stop using such eye drops and call your doctor if you experience any other eye symptoms such as pain, changes in vision, pupil dilation, or excessively watery eyes when you are not watching the movie The Notebook. It's easy to see that ingesting it is in fact poisoning. If you suspect someone has ingested tetrahydrozoline, do not try to make the person vomit it back up as that may actually increase their absorption of the chemical. Such interactions may enhance the therapeutic effects of the drug or other medications being taken, resulting in undesired side effects (such as an overdose). Saturday's installment of "48 Hours" examines the strange case of Lana Clayton, a nurse who fatally poisoned her millionaire husband by lacing his drinks with Visine. The Houston Chronicle. Symptoms include: Vomiting Ataxia Panting Loud breathing sounds Shaking Hyperactivity Nervousness Weakness Depression Gastrointestinal upset Agitation Lethargy Change in blood pressure Just look at some recent eye dropping news. Internally they also induce vasoconstriction (as Toxnet calls it). Consuming tetrahydrozoline has several unpleasant symptoms, none of which typically include diarrhea. A Franklin woman allegedly stole thousands of dollars from a family friend she was caring for, fatally poisoned her with eyedrops, and staged the scene to . The College of Public Health & Health Professions (PHHP) is dedicated to providing excellent educational programs that prepare graduates to address the multifaceted health needs of populations, communities and individuals. Some reports show that patients who ingest tetrahydrozaline have severe drops in blood pressure and heart rate, which may seem counterintuitive, considering eye drops are meant to constrict blood. "Man Allegedly Poisons Woman with Visine Eye Drops." The following information is helpful for emergency assistance: However, DO NOT delay calling for help if this information is not immediately available. They said they are "shocked and mortified by the cause of Steven's death All our family and friends know how much he loved his wife and how devoted he was to her. Knowles H. Officials said he died in a fall. The Washington Post. In: Burns MM, ed. York County Sheriff's Office, via Associated Press. When consumed orally, tetrahydrozoline passes quickly through the gastrointestinal tract, rapidly reaching the blood and the central nervous system, the article said. 16 September 2008. Clinical rotations in all the major disciplines are provided for UFCOM undergraduate medical students and elective rotations to students from other accredited schools. Dont do most things that he did. General information: Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48 hours after the accident. Remember that movies are not the same as real life: these products do not cause diarrhea, but they may cause life-threatening health issues and even death after people drink them. Nunnally, Derrick. Freeman, Mark. This national hotline will let you talk to experts in poisoning. follows rigorous standards of quality and accountability. Associated Press. Snejana Farberov That's when detectives told Kurczewski about the tetrahydrozoline the . Teenagers and adults who drink larger amounts may also experience heart rhythm abnormalities and breathing problems that can be life-threatening. Symptoms of tetrahydrozoline poisoning include: Blood pressure changes; Nausea; Vomiting; Seizures; Coma; Difficulty breathing; Xiidra does not contain tetrahydrozoline, but is still considered potentially harmful when swallowed. It would be helpful if the following information is readily available: Type, dosage and time of administration of medication, And, the overall health status of the individual. Common Symptoms of Low Grade Arsenic Toxicity. UF Health Neuromedicine Neuromedicine Hospital, College of Public Health & Health Professions, Clinical and Translational Science Institute, Center for Health Equity & Quality Research, Find Information on Medical Conditions & Services, College of Public Health & Health Professions (PHHP), Clinical & Translational Science Institute. As the North Carolina Department of Insurance (NCDOI) indicated, these circumstances led to an investigation by the NCDOI, the Gaston County (NC) Police Department, and Homeland Security Investigations (HSI) that then resulted in allegations of fraudulent life insurance claims. or. Accessed June 8, 2021. The signs and symptoms of Tetrahydrozoline Poisoning may include: First Aid tips for Tetrahydrozoline Poisoning: The emergency medical health professional might perform the following steps towards treating the condition: First aid for Tetrahydrozoline Poisoning is administered by healthcare professionals. by Roberto Machado Noa/LightRocket via Getty Images). The person may receive: Survival past 24 hours is usually a good sign that the person will recover. Milwaukee Journal Sentinel. 2004 Oct;27(3):313-4. Scared of Eye Drops? Lee BY. 746-746). In our patient there was an initial hypertension and bradycardia, followed by a persistent orthostatic hypotension. Before we move further to the symptoms of poisoning and analyze the tests required for its treatment, it's essential to understand the causes and risk factors that can lead to poisoning. Over a three-day period in 2018, a woman in South Carolina secretly added enough eye drops to her husbands water for the active ingredient in the medicine to kill him, according to court filings and officials. Imidazolines (like oxymetazoline and tetrahydrozoline) are commonly found in over-the-counter eye drops and nasal sprays. ", Murdaugh Murders Timeline: Investigations, Deaths and the Collapse of a Powerful South Carolina Family, 8-Year-Old Arkansas Boy Raises More Than $65K for His Favorite Waffle House Waiter, Who Walks Miles to Work, Bryan Kohberger Decries 'Pervasive and Grotesquely Twisted Nature' of Idaho Murders Coverage in Court Document, Family Discovers Kentucky Vacation Rental House Has Secret Underground Bunker and Was Site of Grisly Murder, Lindsay Clancy: Timeline of Events in the Case of Massachusetts Mom Accused of Killing Her 3 Children, Fiance of Slain Orlando TV Reporter Plans to Have His Baby After Harvesting His Sperm Post-Mortem. This site complies with the HONcode standard for trustworthy health information: verify here. Visine is clearly labeled for external use only and should never be swallowed.. Updated by: Jacob L. Heller, MD, MHA, Emergency Medicine, Emeritus, Virginia Mason Medical Center, Seattle, WA. As a subscriber, you have 10 gift articles to give each month. Yet all is not well in revenge land. One drop can be beneficial, one swig can be deadly: tetrahydrozoline intoxication. One of her public defenders, Bryson J. Barrowclough, said in a telephone interview on Friday that Ms. Clayton had testified that she had put only one dose in his water and then tried to kill herself. 35; pp. This page was last edited on 6 February 2023, at 16:47 (UTC). 16 February 2002. 16th ed. Dont say wow so often. 19 June 2009. A 19-year-old Wyoming woman accused of poisoning her stepmother with eye drops has pleaded no contest to an aggravated assault charge. According to police, Unger confessed to poisoning her 3-year-old son by putting Visine in his water bottle and juice bottle (the boy was hospitalized several times but survived) and also causing her 1-year-old son to fall ill when he accidentally consumed the poisoned drinks she had made for his brother. Steve and Lana Clayton lived . All local poison control centers in the United States use this national number. New York Eye and Ear Infirmary of Mount Sinai, The Blavatnik Family Chelsea Medical Center, Heart - Cardiology and Cardiovascular Surgery, Mount Sinai Center for Asian Equity and Professional Development, Preparing for Surgery and Major Procedures, Changes in blood pressure (high at first, low later), The name of the product (ingredients and strengths if known), ECG (electrocardiogram, or heart tracing), Fluids through the vein (intravenous or IV). In exchange, prosecutors have agreed to recommend a sentence of up to four years in the Wyoming Women's Center. Help is available online with web POISON CONTROL or by phone at 1-800-222-1222. Tetryzoline. Tetrahydrozoline or tetryzoline is an alpha agonist (substances that help blood vessel constriction) found in certain eye drops and nasal solutions. Reviewed by: Jacob L. Heller, MD, MHA, Emergency Medicine, Emeritus, Virginia Mason Medical Center, Seattle, WA. is among the first to achieve this important distinction for online health information and services. The following information is helpful for emergency assistance: However, DO NOT delay calling for help if this information is not immediately available. Thank. Visit MyUFHealth to get an estimate for your cost for the most common medical procedures. She had suffered from PTSD attributed to domestic abuse, he said. We offer a a four-year Doctor of Veterinary Medicine programs as well as M.S. Tetryzoline (also known as tetrahydrozoline) is a drug used in some over-the-counter eye drops and nasal sprays. In an online newsletter, titled Red-Eye Drops: Poisonous to Drink, Safe If Used Correctly, it said that intentionally or accidentally drinking eye drops could lead to toxic blood levels. Approved by: Krish Tangella MD, MBA, FCAP. Ingesting this substance can lead to a variety of harmful side effects such as dramatically lowering body temperature, causing severe breathing difficulty, respiratory failure, blurred vision, nausea, vomiting, blood pressure fluctuation, tremors, seizures and even coma. Yin S. Over-the-counter cough and cold preparations: Approach to pediatric poisoning. An act of spite that forces the victim into making repeated visits to the john is regarded as not only extremely inconveniencing to him, but degrading as well. 17:24 GMT 22 Mar 2013 Editorial team. Symptoms of poisonings. Then theres the case of Joshua Lee Hunsucker, a former paramedic in North Carolina, whos been charged with first degree murder, as described by Mark Price for the Charlotte Observer. Tetrahydrozoline is a form of a medicine called imidazoline, which is found in over-the-counter eye drops and nasal sprays. There it can get. If the victim is not breathing, perform mouth-to-mouth resuscitation. Clinical Toxicology, 52(5), 454-469. The departments criminal investigations unit had received a complaint from a family member because of the insurance claim and that is why we investigated it, he said. Jennings reportedly admitted to the crime when she was interviewed by deputies, telling them she wanted her stepmother 'gone.'. Seek medical help right away. Eye drops go in your eyes. 14 November 2006. Significance of the imidazoline receptors in toxicology. Ive reached out to Visine and Johnson & Johnson for comment on these cases. Swallowing this substance can result in a number of nasty effects, including: Pfizer's cautions to users of Visine include: "If swallowed, get medical help or contact a Poison Control Center right away." The victim spent several days in the hospital recovering from reactions to the poisoning that included a dangerously low heart rate and blood pressure. Children are most at risk of Visine poisoning Most cases of poisoning are not criminal, but accidental by children or pets who find the small bottles of odorless, clear solution. To avoid mishap one probably ought to take 150% the minimum lethal dose. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. We are no longer accepting comments on this article. 2018 Sep 5. MILWAUKEE Prosecutors have accused a suburban Milwaukee woman of killing her friend by poisoning her with eyedrops. In young children, serious adverse events can occur from ingesting only a small amount (1 to 2 mL, or several drops) of tetrahydrozoline. You can call for any reason, 24 hours a day, 7 days a week. Medical literature reports other cases of small children brought to the brink of crisis by ingestion of tiny amounts of over-the-counter eye drops. Its a different story if eye drops go down your mouth. . Always read the label before using any over-the-counter (OTC) product. If the cause is not obvious or not minor, see your doctor as soon as possible, especially if there are accompanying symptoms such as loss of vision or the presence of a harpoon. Tetrahydrozoline poisoning occurs when someone accidentally or intentionally swallows this product. Apparently, her death had a sweetheart of an insurance pay-out: $250,000. 2020 Jan 18. So if youve got children or very small actors around, make sure that you keep eye drops safe and secure. In Clinical Toxicology (Vol. Both options are free for the public, and available 24 hours a day. A 19-year-old Wyoming woman accused of poisoning her stepmother with eye drops has pleaded no contest to an aggravated assault charge. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Intentionally or accidentally drinking eye drops can lead to toxic blood levels. Because tetrahydrozoline ingestion can cause significant toxicity in young children, it is very important for parents and caregivers of young children to be aware of this potentially very dangerous poison. 9 January 2009. Tetrahydrozoline causes constriction of blood vessels when it is applied directly on the eye; this reduces eye redness. Watch out for any symptoms that occur beyond your eyes including a headache, dizziness, anxiety, chest pain, shortness of breath, or irregular heartbeats.
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