Theres some evidence that Pycnogenol acts similar to a sustained-release formulation. Rating: 100%. Here are the many health benefits believed to be possible with Pycnogenol: Reduces "leaky" blood vessels by making the wall proteins (collagen, elastin) more resistant to damage. So it . We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. DOI: Dvorkov M, et al. However, healthy people are not immune and can also develop mild infections, in particular after being in improperly chlorinated hot tubs or swimming pools. Pycnogenol is the registered trademark brand name of French maritime pine bark extract. A 2021 review in the Arab Journal of Urology listed it first among "promising herbal remedies" for ED. Regardless of what youre using it for, its best to start with the lowest possible dose. We avoid using tertiary references. 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However, some of these other pine bark extracts can have different active compounds, which may affect their biological activity. 1. This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. Remember to speak with a doctor before taking Pycnogenol. It should never be used as a replacement for approved medical therapies. Pycnogenol has four main components that contribute to its benefits for men's health. Because of its anti-inflammatory effects, nattokinase has been used to help with pain from arthritis, including that of rheumatoid arthritis. Joe Cohen flipped the script on conventional and alternative medicine and it worked. This condition can be temporary or permanent however, some studies have indicated that pine bark extract may help alleviate these symptoms due to its high presence of antioxidants. The active ingredients in pycnogenol can also be extracted from other sources, including peanut skin, grape seed, and witch hazel bark. If you are thinking of taking Pycnogenol for a serious health condition like asthma or high blood pressure, check with your doctor., People who have autoimmune conditions like multiple sclerosis or lupus should talk to their doctor before trying Pycnogenol. In a double-blind, placebo-controlled, randomized, crossover study, 50 patients with erectile dysfunction (ED) were treated with either L-arginine plus Pycnogenol or placebo for a month. In one clinical trial of 156 osteoarthritis patients, pycnogenol reduced pain, stiffness, swelling, and improved joint function after 3 months. Start with a low dose so you can be sure it doesnt cause any side effects. In the study, it reduced cold symptoms and complications, the number of lost working days, and the use of over-the-counter medications compared to those who did not supplement with the extract [60]. Pine bark extract has been studied regarding its relationship to exercise performance, oxidative stress and inflammation to body that has been imposed by exercise. Pycnogenol is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France and is found to contain a unique combination of procyanidins . Pycnogenol lotions applied postirradiation reduced this immunosuppression to 22% (0.05% Pycnogenol) and 13% (0.1% Pycnogenol). Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. Is Garcinia Cambogia Safe for Weight Loss? (8). Inhibits platelet aggregation like low-dose aspirin. A 2017 review reported on the many benefits of using pine bark extract to reduce the effects of aging on skin. Taking pine bark extract also increases the blood . There are several causes for erectile dysfunction, such as neurological and psychological issues. But a month after pycnogenol was stopped, the symptoms came back, suggesting that it may need to be used regularly to achieve the benefits [41]. Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. As a skin cream, its safe to use for about seven days. Pycnogenol led to a reduction of muscle cramps from 4.8 a week to 1.3 at week four. A number of clinical trials suggest that Pycnogenol may lower blood glucose if taken daily for at least 12 weeks. (1, 2). Clinical research suggests that Pycnogenol is possibly effective for improving athletic performance. Some health benefits of Pycnogenol include:. Debra Rose Wilson, PhD, MSN, RN, IBCLC, AHN-BC, CHT. A systematic review of 14 studies found that Pycnogenol gum or mouthwashes may reduce dental plaque, but the quality of evidence is low [58, 59]. Pycnogenol (100 mg/day) improved menopausal symptoms and quality of life in a clinical trial of 35 women after 8 weeks [68]. A 10 week clinical trial with 30 children shows that Pycnogenol may improve symptoms of Crohns disease. While the aspirin reduced the risk for cardiovascular disease and colorectal cancer, among other cancers, the risk of gastrointestinal bleeding outweighed those benefits, creating more risks to the body. It has been studied for its effects on everything from mental function to treating high blood pressure. The researchers concluded that pine bark extract may increase production of hyaluronic acid and collagen, which are both found in many popular antiaging products. One study of 211 found that Pycnogenol may help prevent edema and ankle swelling from long flights [27]. In combination with Mirtoselect, Pycnogenol may improve blood flow to the eye and reduce eye blood pressure as shown in a trial of 38 people [81]. In the study, women taking Pycnogenol were more satisfied and compliant to the regimen [24]. Regardless, a natural option is available and far worth the wait. Learn more. It also lessened the amount of asthma medication they needed. . Pycnogenol can help control blood pressure, which helps improve overall heart health. All included participants had subclinical cognitive impairment, which looks like typical brain fog [22]. Therefore, those who have autoimmune conditions could see their symptoms increase after taking it., Since Pycnogenol is used for so many conditions, doses can vary. Pycnogenol is officially extracted from the French maritime pine (Pinus pinaster), which grows in the southwest coast of France. A review was conducted of French maritimepine bark extract, specifically using the nutritional supplement Pycnogenol. Make sure to seek out the advice of your physician prior to using pine bark extract or the branded name, Pycnogenol. Moreover, Pycnogenol lowered the chemical, leukotrienes responsible for asthma attacks. Tell your doctor about any supplements you're taking, even if they're natural. A 2011 study by Dr. G. Belcaro concluded, " Pycnogenol administration was effective for better control of signs and symptoms of allergic asthma and reduced the need for medication". Another group of men who took just l-arginine didnt improve [66]. In the placebo group, the retinopathy worsened; whereas, in the Pycnogenol-treated group, there was no deterioration. Pycnogenol reduced foot swelling in 79% of the patients, versus one percent in the placebo group. What gives pine bark extract its notoriety as a powerful ingredient and super antioxidant is that its loaded with oligomeric proanthocyanidin compounds, OPCs for short. The standard dose appears to be 100-200 mg/day. What Are These Tiny Red Spots on My Skin (Petechiae)? It can also be used for local application on the skin without the risk of side effects. Studies were conducted in Turkey on subjects who underwent abdominal surgery to determine if the pine bark extract could help reduce the inflammation. You may want to start slow, taking smaller amounts, to ensure that your body works well with the OPCs found in pine bark extract. In one study, 10 patients were treated with placebo and 30 patients were treated with Pycnogenol (100 mg twice or three times daily for two months). The staff there can often answer any questions you have and give you more information about specific brands. In contrast, bleeding still occurred in the control group [61]. In 19 smokers, increased platelet aggregation was more significantly reduced by 200 mg than either 10 mg or 100 mg of Pycnogenol. From diabetes and sexual function to sports performance and beautiful skin, pine bark extract may be worth exploring to provide results youre looking to achieve. She is a strong advocate of integrating scientific knowledge and holistic medicine. During the first month on L-arginine, only five percent of patients experienced normal erection. For mild high blood pressure: 200 milligrams daily. , Improves Symptoms Associated With Menopause, A number of women experience physical discomfort due to symptoms of menopause. Can Pycnogenol help? The supplement significantly reduced hot flashes, night sweats, mood swings, irregular periods, loss of libido, and vaginal dryness. Disease of the retina in the eye. A combination supplement (pycnogenol with collagen, coenzyme Q10, and other ingredients) reduced skin aging, elasticity, hydration, and tonicity in a study of 30 women [65]. We take a look at what the science actually says. While much of this is positive, it will be a while before doctors routinely recommend this dietary supplement for these conditions. However, research on these two groups is limited [71, 15]. The top benefits of nattokinase include the following: Regulate blood pressure. You can learn more about how we ensure our content is accurate and current by reading our. It can also be found as creams, lotions or ointments, typically containing 0.5 percent to 2 percent pine bark extract. The flesh of the grape contains approximately 1/20th-1/100th of the total antioxidant capacity of the seed or the skin. Researchers suggest that it may have stronger benefits than elastic compression stockings. It also provides powerful antioxidant protection and helps inhibit inflammatory factors to support. Taking pycnogenol daily for 2 months seems to slow or prevent further worsening of retinal disease caused by diabetes, atherosclerosis, or other diseases. Some people who have asthma have higher levels of leukotrienes in their blood. Possible side effects . Moreover, Pycnogenol treatment led to an increase in sperm count and testosterone levels with lowering of blood pressure and cholesterol levels. Early research shows that taking it at least 5 weeks before the start of allergy season seems to lessen symptoms. Additionally, the results showed that the extract has significant anti-pseudomonas activity, making it a potential natural remedy and possible preventive measure for infections. If you take any medications regularly, talk to your doctor before you start using pycnogenol supplements. They include: We need more research to know for sure if pycnogenol helps treat these conditions. A randomized clinical trial of 30 people found that Pycnogenol (150 mg/day) may help heal vein ulcers from surgery and reduce swelling after 3 months of treatment [25]. Pycnogenol has not been found to cause these issues however, it may take a little longer the feel the relief from pain than aspirin. A study of 147 people found that pycnogenol (100 mg/day) may improve running, push-ups, and sit-ups endurance in recreational athletes over an 8-week training program. For children with ADHD, research suggests that symptoms start to return after about a month without taking maritime pine, so taking periodic breaks shouldnt make it any less effective. If you choose to use Pycnogenol, follow the dosage instructions on the label. After stopping Pycnogenol for one month, symptoms Unlike drug manufacturers, the makers of supplements dont have to show their products are safe or effective before selling them on the market. In another study, 61 children with ADHD were given one mg per kg/day of Pycnogenol or placebo over four weeks. Pycnogenol significantly reduced the swelling as well as the feeling of heaviness. Pycnogenol also treatment improved blood vessel function. This bark extract has been around for about 450 years. In 22 German heavy smokers, platelet aggregation was prevented by 500 mg of aspirin or 100 mg Pycnogenol. Pycnogenol French maritime pine bark extract's 4 basic properties. Consequently, blood pressure is lowered. A randomized placebo-controlled trial of 60 children with mild-to-moderate asthma found that those who took Pycnogenol may be able to reduce or discontinue their use of rescue inhalers more often than the placebo group [15]. Note that each number in parentheses [1, 2, 3, etc.] Trees of this pine have been naturalized in Australia and New Zealand, where most Enzogenol is now made [7]. According to some researchers, when you take Pycnogenol [8]: Research suggests that Pycnogenol may protect cells in the body against oxidative stress. Commonly called arthritis, osteoarthritis is caused when the cartilage on your joints begins to wear down. WebMD does not provide medical advice, diagnosis or treatment. This plant extract also shows promise in such far-flung conditions as traumatic brain injury 40,41, skin problems 37, pain syndromes 38,39, and even tinnitus . 1. This makes it very hard to set a standard dose. Staves Off Infections. Talk to your own doctor about Pycnogenol if youre interested in using it for your own health. A clinically studied blend of Pycnogenol and a special bilberry extract (called Mirtogenol ) has been shown to provide benefits for vision and eye health. This review noted that pine bark extract may also help with: In addition to its skin-healing properties, pine bark extract also shows promise for helping children manage ADHD symptoms. By clicking Subscribe, I agree to the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, Becoming a Vegetarian: Foods to Choose From. Enzogenol, a slightly different pine bark extract, may help improve brain function after mild concussions. Still, more research is needed to better understand these findings and pine bark extracts role in reducing damage from head trauma. The goal of one study was to evaluate whether or not Pycnogenol could prevent edema (fluid build-up) during long-haul flights in healthy people. Also, be sure to talk with your doctor first if you have an underlying medical condition or take other medications. For diseases of the retina, including those related to diabetes: 50 milligrams three times daily. Chemistry. Pine bark distill has been studied regarding its relationship to exercise performance, oxidative stress and excitement to torso that has been imposed by exercise. It also slightly decreased blood pressure and increased testosterone [67]. The combination of L-arginine and Pycnogenol may help in erectile dysfunction by boosting nitric oxide, which potentially could improve blood flow in men [66]. These antioxidants scavenge those damaging free radicals in an effort to eliminate them, ultimately preventing disease. Neuroprotective effect of Pycnogenol® following traumatic brain injury. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. Pycnogenol alleviated adverse effects in cancer patients, Pycnogenol improved working memory in older adults, Pycnogenol lowered the use of analgesic drugs in dysmenorrhea (severe menstrual pain), Pycnogenol reduced symptoms in endometriosis comparable to leuprorelin, the standard drug for this condition, Pycnogenol was found to be effective for sun-caused hyperpigmented skin, Pycnogenol reduced the inflammation in lupus patients, Pycnogenol reduced gingival bleeding and plaque formation. Enzogenol also may reduce mental fatigue and sleep problems [82]. Another 2006 study examined the effects of the antioxidant activity of pine bark extract on oxidative stress, which is thought to be one of the nongenetic factors contributing to ADHD. Researchers suggest that Pycnogenol may reduce cough, night-awakenings, improve airway flow, and the need for additional asthma medication [16]. She loves communicating science and empowering people to achieve their optimal health. Infants and children may not be able to synthesize enough of it, but it is present in many protein-rich . Pycnogenol-treated subjects experienced an improvement in all menopausal symptoms. It also reduced LDL cholesterol at a slightly lower dose (125 mg/day) in those with type 2 diabetes in a clinical trial of 48 people after 12 weeks. The 2012 study on the anti-aging benefits of Pycnogenol is commonly-cited by anti-aging supplement manufacturers. Chewing gum with Pycnogenol (2.5 mg/piece) for 4 weeks reduced bad breath and mouth bacteria in a trial of 22 people [57]. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Tongkat ali is an herbal remedy suggested to treat various ailments, including low testosterone and male infertility. But, as you know, going for the natural approach can make a huge difference in overall health. Depending on the extraction process and the source Pinus species used (P. radiata or P. pinaster), the exact composition will vary. Pine bark extract can make a great addition to your nutritional arsenal for its potent antioxidant support, as well as its added support for blood flow, blood sugar, inflammation, immunity, brain function and skin support. A small 2017 study examined the effects of pine bark extract in treating cardiovascular risk factors associated with menopause. Research into Pycnogenol has revealed some promising results in over 30 health conditions. The same study showed that a single, 200-mg Pycnogenol dose remained effective over six days in preventing cigarette-induced enhanced platelet aggregation. (3), Ototoxicity is ear poisoning and can occur when exposed to certain drugs or chemicals, such as cisplatin, that damage the inner ear or the vestibulocochlear nerve. Almost 400 years later, Dr. Jacques Masquelier from France came across Cartiers account and started to look for the active ingredients from the bark of the tree. This includes supporting healthy blood circulation, acting as a natural anti-inflammatory, helping to generate collagen and hyaluronic acid for improved skin health and aiding in the production of endothelial nitric oxide which helps to dilate blood . He learned about the seemingly omnipotent antioxidant within it and how those antioxidants increase the absorption of vitamin C. Continued research showed that the pine bark contained flavonols and bioflavonoids, which hold tissue-repairing properties. Mental function. 5) Inflammation and Allergies. They were treated with 200 mg of Pycnogenol daily or with placebo. Discover what the research says about elimination diets, foods to eat, and more. After taking a break for one to two weeks, they can start taking it again for several weeks. The combination of Panax ginseng and vitamin E also appears to have an effect. Blood pressure is an important measure of how much blood is pumping from your heart to the rest of your body . Treatment of ADHD with French maritime pine bark extract, Pycnogenol [Abstract]. Pycnogenol may stimulate the immune system. Pycnogenol acts as a sustained-release formulation. ( 1) 2. Pycnogenol has given indications that it might be able to benefit heart and artery health, to include reducing high blood pressure. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. High-dose Pycnogenol (360 mg/day) for 4 weeks had the same LDL-lowering benefits in another study of 40 people [32, 56]. Although the preliminary studies show many health benefits with the use of Pycnogenol, future larger and better studies are needed. Upset stomach. It seems to lower blood pressure and improve blood flow to the legs. There is limited evidence that it could be used in treating Attention Deficit Hyperactivity Disorder (ADHD). If you are taking blood thinners, do not take pine bark extract or Pycnogenol unless approved by your doctor. Various studies, referenced at uofmhealth.org, have shown that a daily dosage of Pycnogenol . However, its always a good idea to start with a low dose so you can monitor how your body responds. It can also stabilize mast cells, which release histamine and trigger allergic reactions. The treatment was four 50 mg capsules of Pycnogenol. A sitz bath, which involves sitting in warm water for 10 minutes, twice daily, is helpful to patients with anal itching, aching or burning and is known as one of the best ways to get rid of hemorrhoids fast. In a study of 61 ADHD children, pycnogenol reduced hyperactivity, improved attention, and motorics after 1 month. The study showed that many people who participated had a drop in their systolic blood pressure after taking Pycnogenol. 5) Vein Diseases and Swelling. Furthermore, when CHS was suppressed by 71% with exogenous treatment with cis-urocanic acid, the putative epidermal mediator of photoimmunosuppression, 0.2% Pycnogenol lotion reduced the immunosuppression to 18%. Required fields are marked *. We do not aim to diagnose, treat, cure or prevent any illness or disease. This ensures that there is a healthy flow of blood to and from the heart. Posted on Thursday, August 14, 2014 The majority of this article is information obtained from the book "All About DIM" by Michael A. Zeligs, MD and A. Scott Connelly, MD. A 2006 study found that children who took a daily pine bark extract supplement for four weeks had significantly lower levels of hyperactivity. This article reviews tongkat ali, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Once youre sure that you dont have any negative reactions, you may be able to increase your dosage according to the label. Another study in 2012 showed that Pycnogenol alone, at a dose of 75 mg/day, increased skin hydration by 8% after just 6 weeks; in women with dry skin at baseline the increase was 21%. Take Helpful Supplements. However, a study of 24 adults with ADHD found that pycnogenol did not improve ADHD symptoms better than placebo. The antibacterial activity was assessed indicating that the essential oil of pine bark, specifically the proanthocyanidins, were effective against P. aeruginosa, significantly inhibiting its growth. L-arginine is more effective when paired with L-citrulline or pycnogenol to combat erectile dysfunction and improve exercise performance. It had the best results when combined with compression stockings, but worked just as well alone [28]. Some pycnogenol supplements are mixed with other antioxidants, such as vitamin C. Pine bark extracts other than pycnogenol are also sold. In 7 volunteers, Pycnogenol (300 mg) for 5 days may reduce the activity of a crucial inflammatory gene (NF-B) [53]. In a third study, 19 men with fertility problems were given 200 mg Pycnogenol daily for 90 days. nausea. This supplement possibly activates the immune system. With time, the participants were able to handle more UV radiation without experiencing skin damage [63]. $109.99. Natural Factors Pycnogenol 25mg 60 Veggie Caps. In another study, Pycnogenol increased glutathione levels and total antioxidants after a month in children with ADHD [42, 43]. According to a study of 11 patients with lupus, pycnogenol may reduce symptoms, inflammation, and oxidative stress [54]. Pycnogenol seems to help with asthma and allergies. A trial of 39 people with hay fever found that Pycnogenol may reduce nose and eye symptoms. Pycnogenol (200 mg/day) may reduce muscle cramps and pain according to a study of 66 healthy people, athletes, and those with venous problems after 4 weeks. Potential benefits of folic acid include a reduced risk of cancer, improved cognitive function, stronger bones, enhanced heart health, better pregnancy outcomes and reduced symptoms of restless legs syndrome. Results showed that one month of Pycnogenol led to a significant reduction of hyperactivity with improvement in attention and visual-motor coordination and concentration, as compared to no positive effects in the placebo group. The first studied group included 66 healthy subjects in whom the number of muscle cramps was recorded two weeks before entering the study and during the fourth and fifth week. In another good study, 48 patients with diabetes and high blood pressure on ACE inhibitors were randomized to receive either Pycnogenol 125 mg daily or placebo for 12 weeks. Perimenopausal women who took pine bark extract for eight weeks noticed decreased cholesterol and triglyceride levels. Moreover, Pycnogenol treatment reduced the use of painkillers. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at [emailprotected]. Pycnogenol may reduce glucose levels, but it doesnt appear to increase insulin production or insulin sensitivity. (14, 15). Our team includes licensed nutritionists and dietitians, certified health education specialists, as well as certified strength and conditioning specialists, personal trainers and corrective exercise specialists. Diabetes-associated small blood vessel changes is the leading cause of diabetic ulcers. Here are 12 benefits of ginkgo biloba. A deficiency can cause issues like anemia, stunted growth, heart problems and neural tube defects. This nerve affects our balance and hearing by sending signals to the brain. Add to Cart. (13). Four hundred years later, a French researcher named Jacques Masquelier did some studies to understand why this natural remedy was so effective. 5. It comes from the bark of a European pine tree. (4). Fundukian, L.J. Consider pine bark extract through a conversation with your physician or a functional medicine doctor. Pycnogenol may help reduce symptoms of melasma, a form of hyperpigmentation, possibly because it protects against UV rays.
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